1986 Volume 46 Issue 3 Pages 415-421
Clinical study of ten cases with erythroleukemia was performed. Age ranged from 19 to 77 years (average 53) . According to FAB classification, the diagnosis of each case altered during the clinical course as follows ; Case 1 RAEB, Case 2 RAEB→RAEBt, Case 3 RAEBt→M4, Case 4 RAEB→RAEBt→M4, Case 5 RA, Case 6 RAEBt→M1→RAEBt, Case 7 RAEBt→M1, Case 8 RA-RAEB→fibrosis, Case 9 RA, Case 10 RAEB→RAEBt, Cytogenetic study revealed seven cases with major karyo type abnormalities (MAKA type) . None of ten cases obtained a complete remission with chemotherapy. 50% survival was 4.5months. Improved survival was noted in cases which showed LDH revels less than 1000 WU and platelet count more than 5×104/μl. There were no significant correlation between survival and age, hemoglobin level, WBC count, chromosome abnormalities.
