Abstract
Concerning the changes of primary necropsy diagnosis, pathological studies were done on 144 very low birth weight infants. And 104 cases, after NICU induction, were examinaed for pathological findings correlating with the causes of death. 1; The necropsy cases of very low birth weight infants were increasing in the neonatal necropsy cases. 2; After the NICU induction, HMD, BPD, SEH/IVH, infections had increased, whereas aterectasis and massive pulmonary hemorrhage had decreased, in primary necropsy diagnosis. 3; In pathological findings, respiratory disease is still found frequently, and which might suggest on difficulties in respiratory care. SEH/IVH is a significant disease, and increase in numbers. Infections, chiefly sepsis, are increasing rapidly and 90% of them are late onset type. And they are less complicated with SEH/IVH, and have a good possibility of being survived without sequlea unless they are infected. 4; Infections are often find SFD rather than AFD, but HMD and SEH/IVH do not have that of tendency. Anomaly is the significant cause of death for SFD, those birth weights are between 1250-1499 g. 5; The correlation of primary necropsy diagnosis and secondary pathological findings reveals as follows. Pulmonary aterectasis, HMD are primary anoxic pulmonary lesions, which often complicate SEH/IVH, secondary. Severe SEH/IVH as primary necropsy diagnosis often complicate hyaline membrane formation and other hemorrhagic lesions. Infections often complicate pneumonia, BPD, and adrenal hemorrhage.
