Abstract
The aromatic amino acid (AAA) did not change after the treatment of both CHP and PE, however the branched-chain amino acid (BCAA) increased significantly. In the cases that recovered consciousness, AAA decreased, BCAA returned to normal range, molar ratio (MR, BCAA/AAA) and EEG showed the improvement after the treatment of CHP and PE.
It was considered that there were some degrees of interrelation between MR and coma grade and between coma grade and EEG, however, there was no difference between MR and EEG.
Thus, it was suggested that hepatic coma was related to the improvement of BCAA metabolism in the muscle after the treatment of both CHP and PE, and the function of remaining hepatic cells.
It was usefull to use CHP and/or PE together with the special amino acid for the improvement of consciousness in hepatic coma, however, the function of the remaining hepatic cells was the most important.
