Abstract
In the present study, pathology of the pancreas and other organs, and interrelations between organs, were investigated during autopsy and in cases of acute pancreatitis. This pathological investigation revealed close relations between acute pancreatitis, particularly acute severe pancreatitis, and MOF similar to those between infection and MOF. It is thus urgent to establish treatment against shock, renal failure, respiratory disorder, or respiratory failure-pleural effusion, pulmonary atelectasis, ARDS and so on-that might cause early death.