Abstract
Early depressed carcinoma in the fundic gland region of the stomach was studied clinicopathologically to determine if it can develope into scirrhous carcinoma of the gastric body. The subjects were nine patients with early depressed carcinoma (five with m-carcinoma and four with sm-carcinoma) in the fundic gland region of the stomach which was diagnosed and resected in the authors' department. The results were as follows : 1) When the early depressed carcinoma in the fundic gland region of the stomach was examined macroscopically by endoscopy, the depressed surface of the carcinoma focus was irregular in all cases, and the depressed margin showed II c-like malignant findings. 2) The depth of the carcinoma invasion and depth of the ulcer in the carcinoma focus were Ul- II except for one case of m-carcinoma. 3) The invasion morphology in the sm-carcinoma cases was the reverse trapezoidal type (type 1) in three cases, and the trapezoidal type (type 3) in one case. 4) The range of carcinoma invasion and extent of fibrosis in sm cases was carcinoma invasion>fibrosis in one case, invasion=fibrosis in two cases, and invasion<fibrosis in one case. We concluded that the early carcinoma in the fundic gland region of the stomach, which we have resected until now, did not develop into typical scirrhous carcinoma.