Abstract
A clinico-statistical survey was carried out on 154 patients (secondary repair of bilateral cleft lip: 144 cases, primary repair of bilateral cleft lip: 10 cases) who had been undergone Onizuka's One-Scar-Line procedure at the Department of Plastic and Reconstructive Surgery, School of Medicine, Showa University from March, 1975 to December, 1990. 1. Hypertrophic scar formation occurred in 40 cases (27.8%) after this procedure as secondary repair of bilateral cleft lip, and was the most common in the nostril floor area. 2. Hypertrophic scar occurred more on the complete bilateral cleft lip than on the incomplete type, and more on bilateral cleft lip in conjunction without cleft palate than with cleft palate. 3. Hypertrophic scar was more frequent in young patients than elderly patients. 4. Modification of the procedure, such as insertion of a skin flap into the nostril from the alar base of the upper lip, decreased the incidence of hypertrophic scar to 19.0% in 1990. 5. We evaluated the effect of radiation and Tranilast, and found that they were not effective in preventing hypertrophic scar formation after the One-Scar-Line procedure.