Abstract
A 46-year-old male had been treated for duodenal ulcer. Upper gastrointestinal (G. I.) endoscopy revealed a submucosal tumor on the opposite side of the papilla Vatar in the second portion of the duodenum in October, 1991. Biopsy specimens, under endoscopic examination at several sites, showed only normal duodenum mocosa. He suffered melena occasionally from June, 1992, but the melena continued for two days from December 3 to 5, 1992. Emergency upper G. I. endoscopy revealed bleeding from a small ulcer on top of a submucosal tumor. The bleed-ing was stopped by HS-E injection to the mucosa around the ulcer. He received gastro-duodenec-tom y in January, 1993. The submucosal tumor, 2.7×2.0×2.8cm, had developed into the duodenum and revealed a defect of the mucosa in part on the mucosal surface. Diagnosis of the leiomyoma of the duodenum was made because of the tumor was composed of spindled smooth muscle cells withrod nuclei.
