Abstract
174 patients with Helicobacter pylori (Hp) positive peptic ulcers from 1996 (Jan. 1) to 1999 (May 31) were treated with a low dose proton pump inhibiter (PPI) with clarithromycin (CAM), and with metronidazole (MNZ: 1-week treated group and 2-week treated group) or amoxicillin (AMOX: 2-week treated group) . In this study, effective rates of three low-dose treated groups were 87.3% in MNZ: 1-week group, 88.5% in MNZ: 2-week group and 95.5% in AMOX group respectively. Total effective rate of this study was 90.8%. Side effects were recognized in 23%, but all the symptoms were slight. In conclusion, we consider that low-dose therapies for peptic ulcers were effective for antibacterial treatment of Hp infection.
