Abstract
Automatic control of the administration of general anesthesia is considered useful for improving the safety of anesthesia and helping anesthesiologists with monitoring work. Basically, any control system should use multi-variables from various physiological systems, such as cardiovascular, respiratory, central nervous and neuromuscular, to control multi-agents such as anesthetic agents, drugs and fluids. The research currently performed is the beginning of this process, a system for the control of one agent, halothane, by one variable, mean arterial pressure. The control system is a discrete, digital type and is implemented using a small computer. The control algorithm is a combination of two control formulas. One is an optimal control to maintain the actual pressure at its reference level under possible minimum halothane administration, and the other is an adaptive offset adjustment formula to compensate for a time-varying and nonlinear aspects of a system. Results of testing the control system with dog experiments are presented.
