Abstract
This paper describes a design of a feedback control system maintaining the arterial CO2 partial pressure near the normal level by artificial respiration against disturbances such as CO2 production rate, dead space, and blood flow. The controlled system is approximated by a linear model. By its aid a proportional controller with a lag-lead compensator is designed to satisfy the requirements arising from the performance of the biological respiratory system. It has been confirmed by simulation that the control system had good responses to the above-stated disturbances, and that it was little affected by the parameter variations in the controlled system.