Abstract
The transit time distribution through the whole circulatory system is determined from the whole dilution curve which is the record of dye concentration of blood lead from the left ventricle after injection of dye into blood at the aortic root.
When a bolus of a substance is injected in the circulatory system, it is gradually mixed with blood as a consequence of the transit time difference and ventricular mixing. The temporary process of circulatory mixing is quantitatively expressed as the standard deviation of concentration for all the circulatory blood to the mean concentration and is computed with the use of the transit time distribution and the whole dilution curve.
The changes in transit time distributions and processes of circulatory mixing due to heart rates were examined in the experiments with anesthetised dogs during vagal nerve stimulation and extracorporal hypothermia.
