Fractal Dimension Analysis in Self-Assembled Poly(dA)·poly(dT) DNA Network on Mica Surface

Abstract

Characteristics of the self-assembled poly(dA)·poly(dT) DNA network adhered on the mica substrate are experimentally investigated based on the AFM observations and the fractal dimension analysis. Artificial B-type double stranded DNA, which consists of 50 base pairs of adenine and thymine, is specially prepared for the experiment. The manufacturing process of DNA network is done in the aqueous solution of poly(dA)·poly(dT) DNA, and the systematical experimental runs are made for various concentration of the solution. It is found that the 2D fractal dimension strongly depends on the fabrication process of the DNA network.