The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME
Online ISSN : 2424-2829
2015.27
Session ID : 2C23
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2C23 The effect of hypergravity on c-Fos gene expression in prechondrogenic cells
Jeonghyun KIMKevin MONTAGNETakashi USHIDAKatsuko FURUKAWA
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Keywords: Hypergravity, ATDC5, c-Fos
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Abstract
c-Fos is a proto-oncogene that is also known as an early response gene to mechanical stress in various cell types. In this study, we firstly found out that applying hypergravity to pre-chondrogenic ATDC5 cells significantly reduces c-Fos gene expression. Hereby we performed a detailed study of c-Fos expression under hypergravity with regard to intensity and duration of the stimulation.
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© 2015 The Japan Society of Mechanical Engineers
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