The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME
Online ISSN : 2424-2829
2016.28
Session ID : 1A23
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1A23 Experimental Measurement of Thrombus Formation under Fluid Flow in Micro Channel : Effect of Wall Shear Rate
Kazuki KOIKEHiromi MIYOSHIHiroto TANAKAHao LIUKen-ichi TSUBOTA
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Abstract
A clot of enzyme-activated milk in a low flow region was observed as a model of a venous thrombus. The milk was perfused in a micro channel with a custom made perfusion system A wall shear rate was controlled in the range of 10 to 22500 s^<-1>. A straight channel with a square cross section of which an edge length was 400 μm or 1200 μm was used. As a result of experiment, a milk clot formed along a channel wall. An amount of a clot increased with a decreasing wall shear rate when it was smaller than 10000 s^<-1>. On the other hand, an amount of a clot increased with a wall shear rate when it was greater than 10000 s^<-1>. A total mass of milk clot per wall surface area was greater in a wider channel.
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© 2016 The Japan Society of Mechanical Engineers
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