The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME
Online ISSN : 2424-2829
2016.28
Session ID : 1C23
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1C23 A study on artificial cell membrane formed on mesh filter
Keita FURUNOAkihiro MATSUTANIYoshitaka MIYAMOTOTohru YAGI
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Abstract
In living cells, membrane proteins play important roles in cellular activities. Since cell membranes consist of a lipid bilayer, membrane proteins can be incorporated into artificial lipid bilayer, and its membrane can be applied to the analysis of membrane proteins and/or biosensor devices using membrane proteins. Therefore, a technique to form lipid bilayer membrane on a microchannel or a microchamber has been paid attention. In this paper, we propose a new technique to form lipid bilayer membrane on a mesh filter. Filling the water solution in the micropores of the mesh filter by using a microchannel, lipid bilayer membrane will be formed on the filter with contact method. This technique will be useful since the filter can be transferable to anywhere for various experiments. Presently, we develope a MEMS device which consists microchannels and films with micropores. In order to evaluate the micropores, the device is filled with water solution to form the lipid bilayer membrane on the pores, and observed under a microscope.
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© 2016 The Japan Society of Mechanical Engineers
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