Abstract
Cerebral revascularization is a general surgery for vascular lesions. Operative procedures are decided based on surgeon's experience, however unpredictable complications are still a problem. The aim of our study is to predict complications before operation by identifying the mechanism of cerebral hemodynamics adaptations. It is considered that blood flow is regulated for meeting demand of tissue cells. There is a little study about the relationship between blood flow in cerebral arteries and cerebral demand. In this study, the total of flow rate in both sides internal carotid arteries and basilar artery is 'supply blood flow', and gray matter volume (V_G) and white matter volume (V_W) are multiplied by each literature cerebral blood flow (k_G, k_W) to calculate 'demand blood flow' (V_G・K_G+V_W・K_W). For 14 healthy volunteers and 2 patients (aneurysm and ischemic), the ratio of difference between demand and supply blood flow on the basis of supply values are studied. As the result, difference between supply blood flow and demand blood flow is -11.3% in healthy subjects. In a case of aneurysm, difference rate is low before and after surgery. In a case of ischemic, there is a high difference rate (59.1%). However, difference becomes lower (12.1%) by supply blood flow increase after operation. It is suggested that difference rate is available for diagnosis of ischemic.
