Abstract
To analysis platelet deposition on high shear flows, reaction rate of platelet activation is redefined to be the product of agonists and shear rate factors instead of the original only agonist activation model developed by Sorensen et al.. The new model is then applied to orifice flow. It is found that platelet deposition is mainly caused by resting platelets in the flow field and fraction of surface available for platelet-surface adhesion drops rapidly when platelet activation begins.
