Abstract
Calcined bone is attractive as scaffold material for tissue-engineered bones in biocompatibility and low manufacturing cost. However, its bioabsorbability is still unknown. The objective of this study is to investigate the effects of calcination temperature on the bioabsorbability of calcined bone. Bovine compact bones were calcined at 600 ℃ or 900 ℃ for 22 hours and immersed in the simulated body fluid (Ringer lactate solution) at 37 ℃. The bioabsorbability of calcined bone were evaluated by measuring calcium concentration in the simulated body fluid during incubation time up to 3 days. As a result, either calcined bone at 600 ℃ or 900 ℃ decreased calcium concentrations in the fluid. This tendency was more remarkable in the samples at 600 ℃. The result suggests that calcined bone is osteoconductive rather than bioabsorbable.
