Host: The Japan Society of Mechanical Engineers
Name : [in Japanese]
Date : October 25, 2023 - October 27, 2023
The blood flow in the renal microvasculature may be determined by vascular branching geometries that affects distribution of red blood cells. In this study, a two-dimensional particle method simulation of blood flow from the interlobular arteries to the afferent arterioles was performed to clarify the effects of an asymmetric branching geometry on the distribution of red blood cells. In a blood vessel model, an interlobular artery as the parent vessel bifurcated into 10 afferent arterioles as the daughter ones. Red blood cells and blood plasma were considered as blood components. As a result of simulations, red blood cells were attracted toward the daughter vessels. This caused uneven hematocrit distribution over daughter vessels. In the case that all daughter vessels branched in the same direction, the hematocrit decreased toward the downstream; in contrast, hematocrit increased if daughter vessels branched alternately in opposite directions.