The Proceedings of the Fluids engineering conference
Online ISSN : 2424-2896
2006
Session ID : 807
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807 Development of measurement system for DNA unwinding rates by helicase(2)
Koji MIYAZAKIHiroshi TSUKAMOTOKoji KUSANOYasuo AGAWA
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CONFERENCE PROCEEDINGS FREE ACCESS

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Abstract
DNA unwinding rates by a single Ku70 enzyme molecule are obscured in the population average of steady state, bulk phase measurements. Measurements of the exact unwinding rate in a micro-channel can be applied to new treatments for cancer, nano-machines, and so on. In this study we prepare a micro-channel, laser tweezers, DNA with micro-beads, and Ku70 enzyme for development of unwinding rate measurement system.
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© 2006 The Japan Society of Mechanical Engineers
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