Abstract
Stem cell culture has an impressive influence for curing a variety of diseases. This paper presents a fundamental flow analysis in an bioreactor for the stem cell culture for scaling up and mass production. We carried out the flow visualization and Ply measurement in order to inspect the mean stream and its turbulence. It was found that the Kolmogorov's scale was a key factor for control an agglomerate diameter of a cell in the bioreactor. Therefore, we analyzed flow configuration in the rotating disk bioreactor to reveal relation between the main vortex and cell growth.