Abstract
In order to investigate vascular diseases such as cause of atherosclerosis and myocardial infarction, relationships of endothelial cells (ECs) covered with surface blood vessels and blood flow stimulation have been experimentally studied. In the study, ECs were cultured in a straight microchannel with 400 μm width and 88 μm depth made from polydimethylsiloxane (PDMS) and fluid shear stress were measured using by micro particle image velocimetry (μ-PIV) technique. Wall shear stresses on EC surface and shapes of EC were estimated using velocity distributions near surface the ECs were measured varying observed plane in depth direction.
