Abstract
We have been developing a microporous covered stent as a newly device for cerebral aneurysm treatment.This stent has a porous film to control both embolization and rapid neointimal formation.It is expected that the neointimal formation becomes earlier by using much larger pores,but there is a possibility that the covered stent with large pare cannot embolize by increasing inflow from parent vessel.The purpose of this study is estimation of stent embolization and optimization of pore design to ensure compatibility between reliable embolization and controlling early neointimal formation,in-vitro experiment based on flow similarity low has been conducted by using a 2D parent vessel model with a side wall type aneurysm model.The flow visualization result shows that three kinds of flow pattern in the aneurysm were observed namely,viscous shear induced flow,pressure drop induced flow and those coexistence flow.According to PIV result,mean shear rate in the aneurysm after stenting was decreased to less than 1/10 of before stenting.
