FD analysis by transport process of concentration for prediction of thrombus formation adhered to the wall on shear flows

Abstract

This paper describes the analysis of platelet aggregation on orifice flow by dissipative particle dynamics (DPD). DPD is a computational method for simulating platelet aggregation. In this paper, the DPD method is used for predicting platelet aggregation on orifice flow with concentration transport, and the sensitivities of the configuration and parameters on model are discussed. From computational results, it is found that effects of orifice configuration and parameter of interaction force on platelet aggregation are large compared with other factors. It is expected that the DPD will be combined with transport equation of concentration for accurate prediction of thrombus formation with aggregation.