Investigation of powder particles for micro shock tube driven particle injector

Abstract

Currently, instead of the popular injection system which is administered through the needle, a needleless injector has been developed all over the world aiming at reduction of pain, safety, and further convenience. A powder injection device driven by a shock tube was fabricated for the development of a system in which minute drug particles are injected at high speed and administered to living bodies. In this study, in order to investigate the influence of size, density, number and flight velocity of drug particles on penetration into the living body, and the optimum particle condition for powder injection device, visualization experiments were carried out under a few kinds of conditions. Further, numerical analysis was carried out and comparison between the experiment and numerical results was performed.