Abstract
We have developed freestanding bio-friendly nanosheets with a thickness of less than 100 nm for biomedical applications. These nanosheets represent unique properties such as good adhesiveness, amazingly flexibility, and a high degree of transparency. In this lecture, we introduce a series of the bio-friendly nanosheets developing in our laboratory and their biomedical applications. As components of the nanosheets we focused on various bio-friendly polymers, e.g. typical biodegradable polymers such as poly(L-lactic acid) (PLLA). These nanosheets were fabricated by simple processes of spin-coating and a novel peeling technique from the substrate using a water-soluble sacrificial layer. The obtained nanosheets acted as innovative wound dressings for incised organs and burned skin. These nanobiomaterials therefore constitute a promising alternative to conventional therapies and coating/wrapping techniques in biomedical fields.