Abstract
Early detection of fracture risk is important as effectiveness of treatment with bone diseases. Over the years, loss of bone mineral or bone mass has been considered the major cause of bone fractures. However, recent studies suggest that collagen also contributes to bone strength by using physiological and artificial aging bone. It was found that fracture risk is related to not just a simple loss of bone mass, but related to significant changes in the biochemical and physical properties of the collagen matrix. Therefore the microscopic interaction between the mineral and organic material may determine the mechanical properties of bone. In this study, bovine cortical bone specimens with different ages were analyzed by Raman spectroscopy. As the results, Raman spectrum of bovine cortical bone with different mechanical properties with aging showed the different Raman spectrum with aging. The effectiveness of Raman spectroscopy was confirmed as a technique for the mechanical evaluation of bone aging.
