The Proceedings of Mechanical Engineering Congress, Japan
Online ISSN : 2424-2667
ISSN-L : 2424-2667
2012
Session ID : J053041
Conference information
J053041 Molecular dynamics study on self-assembled pattern formation of DNA fragments on HOPG surface covered with cations
Ryousuke NIlHiroshi TAKEUCHIKentaro DOISatoyuki KAWANO
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Abstract
DNA is expected to be utilized for technological applications due to its various characteristics. In our previous studies, self-assembled DNA networks on mica surface are investigated in detail by the use of atomic force microscopy. The mechanisms of self-assembly has also discussed on the basis of theoretical developments and computer simulations. In the present study, network formations of DNA can be observed on highly oriented pyrolytic graphite (HOPG) surface using electrophoresis of MgCl_2 solution as preprocessing, although DNA molecules have negative charges and usually does not adsorb on HOPG surfaces filled with jt electrons. In order to clarify the adsorption mechanism, we develop and perform MD computations using a coase-grained model. As a result, the network pattern formations, in which DNA fragments make bonds and bundle structures, are replicated by our simulations.
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© 2012 The Japan Society of Mechanical Engineers
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