The behavior of star polymer in shear flow was investigated using Multi-Particle Collision Dynamics (MPCD),which is particle-based mesoscale hydrodynamic algorithm. MPCD is a suitable tool for the simulation of complex fluids because it can express both hydrodynamic interaction and Brownian motion, which are not negligible in the simulation of complex fluids. The present study considered the behavior of a star polymer under flow. A star polymer has many brunches interacting each other. In the present simulation a star polymer chain is consist of beads and elastic spring. The simulation was carried out by changing the number of brunches. The numerical results showed that the deformation behavior and conformation of star polymers depended on the number of branches.