Abstract
A Fluid-Structure interaction method has been developed for massively parallel computing. The method is suitable for the direct simulation from medical image data without a mesh generation procedure. The method employs the concept of Volume of Fluid approach for describing the motion of both fluid and solid. The method is further developed to describe the motion of membrane. The method is used to simulate the blood flow containing many red blood cells and platelets. Using this method, multiscale simulation of the initial stage of thrombosis is conducted with the coupling of Monte Carlo simulation for protein-protein (GPlba-vWF) binding.