The Proceedings of Mechanical Engineering Congress, Japan
Online ISSN : 2424-2667
ISSN-L : 2424-2667
2013
Session ID : J026014
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J026014 Cell adhesion on micro-structured fine particles
Iwori TAKEDAArata KANEKOTatsuki SUGIHARARyuuya MASHIKO
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CONFERENCE PROCEEDINGS FREE ACCESS

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Abstract
This work aims to describe about effects of micro-structure on cell selective adhesion. We research to explain the effect through the use of various particles. Polystyrene and silica fine particles are hexagonally packed in 20- 50 μm line-and-space micro-structures for a cell scaffold. An incubation allows most of cells to be successfully adhered on the region of micro-structured particles, while few cells are found on the rest region of glass substrate. Micro-structure composed of 1 μm diameter is effective for selective adhesion in spite of the amount of protein adsorption is equal to 2 μm diameter.
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© 2013 The Japan Society of Mechanical Engineers
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