Abstract
The main role of cardiopulmonary bypass system is working life support device during open heart operation. Oxygenator which is a component part of cardiopulmonary bypass system adds O_2 to blood and removes CO_2. The type of oxygenator which is used most often today is hollow fiber membrane oxygenator which transfers O_2 and CO_2 through micro porous membrane. The design concepts of oxygenator are a low priming volume and a small foreign substance contact surface. The design of oxygenator is carried out by selecting a gas exchange membrane and structure, determining the specification which depends on the company's product concept. JMS original design which has circular pathway was developed based on the concept of "simplification of the blood pathway".