Abstract
Recent years, the drug delivery systems (DDS) require multi-functionality and high functionality. In this study, we synthesized a multifunctional DDS composed of magnetite nanoparticles core and mesoporous silica shell (Fe_3O_4@mSiO_2) for magnetic resonance imaging and hyperthermia. We evaluated the magnetic characteristics and the heat dissipation characteristics of the Fe_3O_4@mSiO_2 nanoparticles. As a result of the magnetic characteristics evaluation, it was confirmed that Fe_3O_4@mSiO_2 nanoparticles had magnetism. The heat dissipation characteristics of the Fe_3O_4@mSiO_2 suspension were also measured by exposing a magnetic field strength and frequency of 5.08 kA/m and 415 kHz respectively. For a specific time, the Fe_3O_4@mSiO_2 nanoparticles exhibited a temperature rise of 20K. These results imply that the synthesized Fe_3O_4@SiO_2 has potential applications in magnetic resonance imaging and hyperthermia.
