Study of methods for stable measurement of extracellular electric potential using electronic sheet

Abstract

We investigated the method for measuring extracellular electric potential stably by using electronic sheet. Electronic sheet is composed of parylene film and electrode. The thickness of electronic sheet we fabricated in this study is only 500 nm. Therefore, it is really flexible. So, it can follow the movement of cardiomyocyte and measure extracellular electric potential. We are thinking of applying it for drug evaluation system. To achieve this, high stability electrode is needed. Therefore. we focused on the configuration of electrode on electronic sheet. It is well known that chromium layer enhances the adhesion force between gold electrode and substrate. In this paper, we report the difference of stability from presence or absence of chromium layer. It is suggested that chromium layer increase the stability of electronic sheet.