The Proceedings of Mechanical Engineering Congress, Japan
Online ISSN : 2424-2667
ISSN-L : 2424-2667
[volume title in Japanese]
Session ID : J0260101
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Evaluation of friction properties of agarose-chondrocyte complex surface
*Yuki DOIYoshinori SAWAETakehiro MORITATetsuo YAMAGUTCI
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Abstract

It is known that the coefficient of friction between articular cartilages is extremely low. And although the structure and constituents of the joints are known, the mechanism of lowering the coefficient of friction is not known. We experimentally reproduce the joints using the articular cartilage tissue model and pseudo joint fluids, and verify the combined lubrication effect. As a method, a chondrocyte-agarose complex prepared by seeding chondrocytes isolated from bovine cartilage tissue on an agarose gel is cultured in a CO2 incubator, ECM are produced by chondrocytes during the culturing period, and accumulated in the agarose gel. The friction characteristics of the surface are evaluated under a slight load with simulatedly prepared synovial fluid as a lubricant. As a result, those with ECM were relatively lower in friction coefficient. However, problems such as lack of ECM and vertical loads not so stable are found.

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© 2018 The Japan Society of Mechanical Engineers
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