The Proceedings of Mechanical Engineering Congress, Japan
Online ISSN : 2424-2667
ISSN-L : 2424-2667
2023
Session ID : F021-1
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Mechanical characterization and manipulation of single cell by MEMS
Kouhei TAKAMURAYuto ASAKURASeiya IWASHITANobutaka Inoue*Momoko KUEMURA
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Abstract

Mechanical properties of cells relate to their growth, such as differentiation and cell mortality, and represent the diseases. Investigating the mechanics of cells will contribute to the diagnosis and the study of regenerative medicine. Multiple properties of cells should provide more broad and precise information to us. We evaluated cell mechanics and gene expression analysis using MEMS tweezers, which can characterize and manipulate single suspended cells. To characterize adherent cells, we developed MEMS with a single probe and validated the device. Call trapping and manipulation of the measured adherent cells were also examined using MEMS tweezers.

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© 2023 The Japan Society of Mechanical Engineers
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