Abstract
Since a growth of a wrinkle gives a severe change in appearance of face, women have a tremendous interest in wrinkles. In past studies, it was clarified that collagen and elastin fibres are concentrated on dermal tissue along the wrinkle on skin in comparison with normal tissue of dermis. This result is one of the biochemical reactions of the dermal tissue toward an extrinsic factor or local mechanical stimulus acting on the skin. It is possible that mechanical stimulus which returns this tissue to the normal condition contributes to the reduction of the wrinkle. This study presents a modeling of the formation of the dermal tissue under mechanical stimulus. Then, computational simulation is performed along with proposed model.