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We investigated the healing behavior of the bone in plate fixation for a diaphysis fracture using growth strain method. The growth criterion parameters of each cortical bone and callus were determined on normal diaphysis bone by applying two-dimensional finite element method. Next, the remodeling shape on the diaphysis fracture fixed by a plate with 4 screws was created using the growth criterion parameters on the strain energy density. Our findings showed that the periphery of diaphysis fracture swelled after cure. Then, it was the best operation method which penetrated the screws to the cortical bone perfectly.