Abstract
By investigating the interactions between Green Fluorescent Protein (GFP) and Si substrates using molecular dynamics simulation, we got the following results. GFP adsorbs on the hydrophobic substrate directly, and on the hydrophilic substrate via water molecules. GFP-hydrophobic substrate attractions are stronger than GFP-hydrophilic substrate attractions. Flexibility of GFP is reduced when GFP adsorbs on the Si substrate.
