Abstract
We developed the hybrid electrical stimulation method to improve conventional electrical stimulation ones. Long-term bed rest patients and astronauts in the space show, disuse atrophy due to microgravity exposed. This hybrid method is highly effective against the disuse atrophy. The hybrid method has features as follows: 1) electrical stimulated antagonist muscles are used to resist volitional contractions of opposing agonists and 2) both muscle contractions can generate a compressive load to the direction of a long axis of bone. We applied this hybrid method on 4 healthy men (23±1 years) for 4 weeks. We found that MVC and BMD increased by hybrid exercise.