An ion flow is the flow which contains ions or micro charged particles. Differential Ion Mobility Analyzer (DIMA) is an analytic instrument of the nanometer-scale chemical pollutants, and its accuracy is influenced by an electric field, fluid drag, Brownian motion, and turbulence. In this research, numerical simulation of ion flow in electric field was performed. The trajectory of ion was calculated by Lagrangian method in consideration of the influence of electric field, fluid drag, and turbulence.