755 Development of an Arterial-Venous, Multi-Scale Computational Mechanical Model
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Most of the CFD-based studies have been focusing exclusively on some specific blood vessels or vascular segments under highly simplified physiological boundary conditions. The cardiovascular system, however, is a closed-loop system where hemodynamics is an integrated result of the complicated interactions and plays an important role in hemodynamic regulations throughout the system. Therefore, a multi-scale hemodynamic simulator capable to evaluate the circulatory system in a synthetical manner is thought to be able to provide a physiologically realistic evaluation on the circulatory functions. A baseline for such a hemodynamic simulator requires development of a global arterial-and-venous tree model on a basis of the blood vessel morphology of the vascular system as well as the vessel-specific biomechanical properties. In this paper we present some preliminary results of a recently established vascular system database, involving 375 blood vessel models of 263 arteries and 112 veins, which are built up based on the Voxel-Man 3D Navigator, and of visualized blood flow patterns in some vessels of the global arterial-and-venous tree model.
