Abstract
Brain tumor cells invade normal cells, without boundary. The purpose of research was to develop a new brain tumor sensor-probe. This paper examines the feasibility of an oligopeptide to sense the brain tumors. By Solid-phase synthesis, a 16mer oligopeptide with fluorescent substance was composed. As a result of refinement, and analysis by high-performance liquid chromatography (HPLC) and Liquid Chromatography-Time of Flight/Mass Spectrometry (LC-TOF/MS) were conducted, I confirmed the composition of the 16mer oligopeptide. When the 16mer oligopeptide dripped on a rat and a porcine brain, a bind reaction with receptor was observed by a fluorescent microscope