The selection of an extremely careful treatment method is requested from the treatment of the aortic aneurysm. In the medical field, the diagnosis by the medical image is used and can easily follow-up. However, there is a limit only by the diagnostic imaging, because the various situations are assumed in aortic aneurysm rupture. We examined about progress, develop and rupture of aneurysm due to aortic dissection using time-series medical images using CFD simulation. As the results, pressures of shape of immediately rupture is higher than former shape and observed the vortex and low wall shear stress in aortic aneurysm. The result showed the factor that effect progress, develop and rupture of aortic aneurysm. Therefore, it is thought that profitable information can be given by combining a clinical diagnosis and this result.