Today an actual human heart shape is easily obtained as a voxel data via medical images. To assist the diagnosis and treatment in daily medical scene, our final goal is the realistic blood flow simulation of an actual heart using the voxel data. Because blood flow is driven by heart contraction and the contraction occurred by cardiomyocyte cell behavior, and the heart shape influences the cell behavior at each time. Therefore it is necessary to consider the fluid-structure interaction driven the cardiomyocyte behavior that is cause of heart wall moving. Although structure behavior is usually simulated based on the Lagrangian frame, we are studying the fluid-structure interaction simulation based on the Eulerian frame. In this simulation, both phenomena flow and structure are calculated by same way based on the same equation in the Eulerian grid. And the force computed by the cardiomyocyte model "Kyoto Model" drives the heart wall contraction. This interaction simulation system simulated a driving blood flow by cardiomyocyte contraction model.