The aim of the present study is to understand the twinning behavior in a commercial pure titanium (CP-Ti) sheet. Stress-strain curves and microstructure evolutions were examined under various loading paths. The activity of twinning was larger under compression than under tension and, moreover, the activity of detwinning was observed during tension following compression. On the other hand, unlike Mg alloys, the effects of the twinning and detwinning on the work hardening behavior seemed to be small.