OS0607 Relationship between Raman Shifts and Compressive Loading of Knee Joint Cartilage
Details
In this study, component analysis as mechanical evaluation was performed by Raman spectroscopy for cartilage consisted by macromolecule (such as collagen fiber and proteoglycan). Raman spectroscopy is a vibrational spectroscopy by Raman scattering, and allows simultaneous measurement of organic and inorganic components. The spectroscopy is suitable for measurement of biological samples because of little effect on water. The cartilage specimens were cut out from bovine knee joint and their Raman spectrum were analyzed under compressive loading. In addition, load response to cartilage by the spectroscopy. The results of Raman shift for hydroxyproline, proline, phenylalanine and Amide I show the mechanical response. Therefore, this study indicated the possibility of stress analysis for cartilage with Raman spectroscopy
