Preliminary experimental study on the mechanical environment of the substrate for cell culture

Abstract

Most cells are significantly affected by the intensity and duration of the dynamic field stimulus due to the culture environment. Therefore, it is important to understand the mechanical environment of an elastic substrate. Therefore, the purpose of this study is to clarify the mechanical environment when the elastic culture substrate is stretched. The displacement field when the elastic culture substrate was stretched was calculated using the digital image correlation (DIC) method. In addition, the strain field was calculated by numerically differentiating the result of this displacement field. From the results, we showed several regions of the maximum strain for the vertical strain components ε_x and ε_y. The strain was roughly uniformed in this range.