The Proceedings of the Symposium on Micro-Nano Science and Technology
Online ISSN : 2432-9495
2013.5
Session ID : 5PM3-PMN-035
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5PM3-PMN-035 Simulation of network formation of microtubules driven by motor protein in liposome
Takahiro NITTAYuichi HIRATSUKA
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Abstract
We present a simulation study on network formations of microtubules and kinesin-streptavidin complexes confined in liposomes. The simulations were performed with a Brownian dynamics simulation. The simulations showed that microtubules formed aster-like networks pointing their plus ends toward the centers of the liposomes they were confined. During the formations, by moving towards the microtubule plus ends, kinesin-streptavidin complexes served as moving crossbridges between two microtubules. Effects of the density of kinesin-streptavidin complexes were also discussed.
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© 2013 The Japan Society of Mechanical Engineers
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