Abstract
This paper reports a novel processing method for protein crystal with electric-induced-bubble. This minimally invasive micro-processing method overcomes the difficulties of processing fragile material such as protein crystal under water. The combination of electrically-induced micro-bubble knife and glass capillary provide effective carving of protein crystal by ablation crystal and suction of chips respectively. Also, we successfully made a new micro-fluidic platform for processing protein crystal. Three-dimensional positioning of crystal was sufficiently achieved by the configuration of effective micro-fluidic channels. The protein crystal can be carved to the desired shape to fit to X-ray analysis effectively.
